Hücre Kültürü Labotatuvarı

Ahmet Oral Sarıoğlu, Hatice Gamze Sogukomerogullari, Ayşegül Köse, Senem Akkoc, Mehmet Sönmez, Mehmet Hakan Morcalı, ‘Novel Eu(III) and Tb(III) Complexes Bearing Carboxamide Ligand: Antiproliferative Activity, Photoluminescence Properties, and Thermogravimetric Studies’ Journal of the Iranian Chemical Society, 2024.

Eyüp Başaran, Reşit Çakmak, Burçin Türkmenoğlu, Senem Akkoc, Semiha Köprü ‘Newly synthesized naphthalenyl-imino-based sulfonamide derivatives as potent anticancer agents with their docking, ADME, DFT, and pharmacophore modeling studies’ Chemistry and Biodiversity, 2024.

Burçin Türkmenoğlu, İrem Bayar, Zülbiye Kökbudak, Senem Akkoc ‘Determination of the Interactions of a Schiff Base with Different Targets via Molecular Docking and Cytotoxic Activity Studies’ Journal of the Indian Chemical Society, 2024.

Halis Karatas, Ebru Onem, Senem Akkoc, Celal Tuğrul Zeyrek, Zarife Sibel Sahin, Zülbiye Kokbudak ‘Antiquorum Sensing Effect, Theoretical, and X-Ray Studies of a Schiff Base Molecule Containing Pyrimidine Nucleus’ ChemistrySelect, 2024. Doi: 10.1002/slct.202402664

Eyüp Başaran, Hatice Gamze Sogukomerogullari, Muhammed Tılahun Muhammed, Senem Akkoc ‘Synthesis of novel Cu(II), Co(II), Fe(II), and Ni(II) hydrazone metal complexes as potent anticancer agents: Spectroscopic, DFT, molecular docking, and MD simulation studies’ ACS Omega, 2024. Doi: 10.1021/acsomega.4c06202

Senem Akkoc, Muhammed Tilahun Muhammed, Zülbiye Kokbudak ‘Synthesis and Molecular Modeling Studies of a New Pyrimidine Derivative’ Indian Journal of Pharmaceutical Sciences, 2024.

Erdem Ergan, Reşit Çakmak, Eyüp Başaran, Suraj N. Mali, Senem Akkoc, Sivakumar Annadurai, ‘Molecular hybrid design, synthesis, in vitro cytotoxicity activi-ty, in silico ADME and molecular docking studies of new ben-zoate ester-linked arylsulfonyl hydrazones’ Molecules, 29, 3478, 2024. https://doi.org/10.3390/ molecules29153478

Ahmed M. Senan, Muhammed Tilahun Muhammed, Senem Akkoc, Sadeq K. Alhag, Eman A. Al-Shahari, Laila A. Al-Shuraym ‘Modification of ionic liquid and lactoferrin-based small molecules as potential therapeutics against SARS-CoV-2: Molecular docking disclosed the predictable results’ Journal of Molecular Structure, 2024. Doi: https://doi.org/10.1016/j.molstruc.2024.139353

Burcu Somturk-Yilmaz, Burçin Turkmenoglu, Senem Akkoc ‘Synthesis, Characterization, Cytotoxic Activity Studies of N1-phenylbenzene-1,2-diamine @CuhNFs and 1,2-phenylenediamine@CuhNFs, and Molecular Docking Calculations of Their Ligands’ Journal of Inorganic and Organometallic Polymers and Materials, 2024. Doi: 10.1007/s10904-024-03178-1

Eyüp Başaran, Semiha Köprü, Senem Akkoç, Burçin Türkmenoğlu, ‘Investigation of Newly Synthesized Fluorinated Isatin-Hydrazones by In Vitro Antiproliferative Activity, Molecular Docking, ADME Analysis, and e-Pharmacophore Modeling’, ACS Omega, 9 (24), 26503–26518, 2024. DOI: 10.1021/acsomega.4c03014

Dicle Sahin, Remziye Aysun Kepekci, Mehran Feizi-Dehnayebi, Senem Akkoc, José Vicente Cuevas-Vicario, Nicola Micale ‘Biological Activities, DFT Calculations, and Molecular Docking Simulation of Thymol-Based Compounds’ ChemistrySelect, 9 (23), e202304572, 2024. Doi: 10.1002/slct.202304572

Firdevs Mert Sivri, Senem Akkoc, Ebru Önem, Esma Uysal ‘Biosynthesis of Ag nanoparticles using Laurus Nobilis L. extract and biomedical applications’ Inorganic and Nano-Metal Chemistry, 1-8, 2024. Doi: 10.1080/24701556.2024.2358339

Eyüp Başaran, Gulal Tür, Senem Akkoc, Tugba Taskin-Tok, ‘Design, synthesis, in silico, and in vitro cytotoxic activities of novel isoniazid-hydrazone analogs linked to fluorinated sulfonate esters’ ACS Omega, 9, 15, 17551–17562, 2024. Doi: 10.1021/acsomega.4c00652

Senem Akkoc, Muhammed Tilahun Muhammed ‘Synthesis, biological application, and computational study of a thymol-based molecule’ Journal of Biologically Active Products from Nature, 14(1), 35-50, 2024. Doi: 10.1080/22311866.2024.2318578

Mohammad Mavvaji, Senem Akkoc ‘Recent advances in the application of heterogeneous catalysts for the synthesis of benzimidazole derivatives’ Coordination Chemistry Review, 505, 215714, 2024. Doi: 10.1016/j.ccr.2024.215714

Eyüp Başaran, Reşit Çakmak, Dicle Sahin, Semiha Köprü, Burçin Türkmenoğlu, Senem Akkoc, ‘Design, spectroscopic characterization, in silico and in vitro cytotoxic activity assessment of newly synthesized thymol Schiff base derivatives’ Journal of Biomolecular Structure and Dynamics, 2024. Doi: 10.1080/07391102.2024.2301747.

Saad Bouchekioua, Senem Akkoc, Rafik Menacer ‘In Vitro and In Silico Studies on Benzimidazole-Based Compounds’ ChemistrySelect, 9(1), e202304347, 2024. Doi: 10.1002/slct.202304347

Dicle Sahin, Remziye Aysun Kepekci, Burçin Türkmenoğlu, Senem Akkoc ‘Biological Evaluations and Computational Studies of Newly Synthesized Thymol-Based Schiff Bases as Anticancer, Antimicrobial, and Antioxidant Agents’ Journal of Biomolecular Structure and Dynamics, 2024. Doi: 10.1080/07391102.2023.2297813.

İrem Bayar, Senem Akkoc ‘A Mini Review on Components of Flax Seed and Their Effects on Breast Cancer’ Journal of Agricultural Sciences, 30(2), 205-215, 2024. Doi: 10.15832/ankutbd.1349777

Sakine Akar, Mustafa Cakir, Ozge Alvur, Halil Ozkol, Senem Akkoc ‘A Benzimidazolium Salt Induces Apoptosis and Arrests Cells at Sub-G1 Phase in Epithelial Ovarian Cancer Cells’ Molecular Biology Reports, 51, 66, 2024. Doi: 10.1007/s11033-023-08981-6.

Senem Akkoc, Dicle Sahin, Muhammed Tilahun Muhammed, Mustafa Yıldız, Ilhan Ozer Ilhan ‘Synthesis, characterization, antiproliferative activity, docking, and molecular dynamics simulation of new 1,3-dihydro-2H-benzimidazol-2-one derivatives’ Journal of Biomolecular Structure and Dynamics, 2024. Doi: 10.1080/07391102.2023.2262601

Mohammad Mavvaji, Muhammed Tilahun Muhammed, Senem Akkoc ‘Synthesis, Cytotoxic Activity, Docking and MD Simulation of N,N-Disubstituted New Benzimidazolium Salts’ ChemistrySelect, 8(43), e202303053, 2023. Doi: 10.1002/slct.202303053

Mohammad Mavvaji, Senem Akkoc ‘Recent Advances in the Anticancer Applications of Benzimidazole Derivatives’, ChemistrySelect, 8(35), e202302561, 2023. Doi: 10.1002/slct.202302561

Ahmed M. Senan, Muhammed Tilahun Muhammed, Laila A. Al-Shuraym, Sadeq K. Alhag, Niyazi A. S. Al-Areqi and Senem Akkoç ‘Synthesis, structure characterization, DFT calculations, and computational anticancer activity investigations of 1-phenyl ethanol derivatives’ Journal of Molecular Structure, 1294, 136323, 2023. Doi: 10.1016/j.molstruc.2023.136323

Reşit Çakmak, Burak Ay, Ercan Çınar, Eyüp Başaran, Senem Akkoç, Mehmet Boğa, Eşref Taş ‘Synthesis, spectroscopic, thermal analysis and in vitro cytotoxicity, anticholinesterase and antioxidant activities of new Co(II), Ni(II), Cu(II), Zn(II), and Ru(III) complexes of pyrazolone-based Schiff base ligand’ Journal of Molecular Structure, 1292, 136225, 2023. Doi: 10.1016/j.molstruc.2023.136225

Dilara Başat Dereli, Senem Akkoç, Ebru Çubuk Demiralay ‘Protonation Constant Determination Of Some Benzimidazole-Based Drug Candidates By Reverse Phase Liquid Chromatography Method And Cytotoxic Activity Studies’ ChemistrySelect, 8(28), e202301192, 2023. Doi: 10.1002/slct.202301192

İrem Bozbey Merde, Gülce Taşkor Önel, Senem Akkoc, Zeynep Karaköy, Burçin Türkmenoğlu ‘Focusing on New Piperazinyl-methyl-3(2H)pyridazinone Based Derivatives: Design, Synthesis, Anticancer Activity and Computational Studies’ ChemistrySelect, 8(25), e202300910, 2023. Doi: 10.1002/slct.202300910

İrem Bayar, Senem Akkoc ‘Antibacterial Activities of Imidazole-Based Compounds (A Review)’ Russian Journal of Organic Chemistry, 59, S7-S19, 2023. Doi: 10.1134/S107042802313002X

Senem Akkoc, Demet Özkır, Eyüp Başaran, Savaş Kaya, Avni Berisha ‘A combined experimental and theoretical approach effect of a benzimidazolium salt as a new corrosion inhibitor on mild steel in HCl solution’ Ionics, 29, 3813-3827, 2023. Doi: 10.1007/s11581-023-05058-z.

Hatice Gamze Sogukomerogullari, Eyüp Başaran, Ahmet Oral Sarıoğlu, Ayşegül Köse, Senem Akkoc ‘Synthesis, characterization, photoluminescence properties and antiproliferative activity of new Pd(II), Ni(II) and Cu(II) mixed complexes bearing Schiff base ligand and 1,10-phenanthroline’ ChemistrySelect, 8 (24), e202301014, 2023. Doi: 10.1002/slct.202301014

Muhammed Tilahun Muhammed, Zülbiye Kokbudak, Senem Akkoc, ‘Cytotoxic activities of the pyrimidine-based acetamide and isophthalimide derivatives: An in vitro and in silico studies’ Molecular Simulation, 49(10), 982-992, 2023. Doi: 10.1080/08927022.2023.2202766.

Muhammed Tilahun Muhammed, Mustafa Er, Senem Akkoc ‘Molecular Modeling and In Vitro Antiproliferative Activity Studies of Some Imidazole and Isoxazole Derivatives’ Journal of Molecular Structure, 1282, 135066, 2023. Doi: 10.1016/j.molstruc.2023.135066.

Soner Akman, Senem Akkoc, Celal Tugrul Zeyrek, Muhammed Tilahun Muhammed, Ilhan Ozer Ilhan ‘Density functional modelling, and molecular docking with SARS-CoV-2 Spike protein (Wuhan) and omicron S protein (variant) studies of new heterocyclic compounds including a pyrazoline nucleus’ Journal of Biomolecular Structure and Dynamics, 41(22), 12951-12965, 2023. Doi: 10.1080/07391102.2023.2169765.

Halis Karatas, Meltem Aydin, Burçin Turkmenoglu, Senem Akkoc, Onur Sahin, Zülbiye Kokbudak ‘Design, Synthesis, Cytotoxic Activity, and In Silico Studies of New Schiff Bases Including Pyrimidine Core’ ChemistrySelect, 8, e20220422, 2023. Doi: 10.1002/slct.202204221.

Celal Tuğrul Zeyrek, Soner Akman, Ilhan Ozer Ilhan, Zülbiye Kökbudak, Emin Sarıpınar, Senem Akkoc ‘Experimental and theoretical studies on 3-(4-chlorophenyl)-5-(4-ethoxyphenyl)-4,5-dihydropyrazole-1-carbonitrile: DFT quantum mechanical calculation, vibrational band analysis, prediction of activity spectra, and molecular docking’ Journal of Molecular Structure, 1276, 134773, 2023. Doi: 10.1016/j.molstruc.2022.134773.

Hatice Gamze Sogukomerogullari, Senem Akkoc ‘Copper(II) complexes with thioether based SNS pincer ligand: Synthesis, characterization and antiproliferative activity’ Journal of Structural Chemistry, 64, 157-167, 2023. Doi: 10.1134/S0022476623010122

Ertuğrul Gazi Sağlam, Elif Bulat, Celal Tuğrul Zeyrek, Senem Akkoç, Yunus Zorlu, Hamza Yılmaz ‘2,4-Bis(2,4-dimethoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide and its derivatives: Syntheses, structural characterizations, anticancer activities, and theoretical studies of a new dithiophosphonato Ni(II) complex’ Journal of Molecular Structure, 1272, 134197, 2023. Doi: 10.1016/j.molstruc.2022.134197.

İbrahim Ozcan, Senem Akkoc, Hakan Alici, Seval Capanlar, Onur Sahin, Hakan Tahtaci, ‘Novel Thioether-Bridged 2,6-Disubstituted and 2,5,6-Trisubstituted Imidazothiadiazole Analogues: Synthesis, Antiproliferative Activity, ADME, and Molecular Docking Studies’ Chemistry & Biodiversity, 20 (1), e202200884, 2023. Doi: 10.1002/cbdv.202200884

Osman Yilmaz, Seval Capanlar, Senem Akkoc, Hakan Alici, İbrahim Ozcan, Hakan Tahtaci, ‘Design, Synthesis, Characterization, Antiproliferative Activity, and In Silico Studies of Novel Alkyl Ether Derivatives Containing 1H-1,2,4-Triazole Ring’ ChemistrySelect, 7(44), e202203604, 2022. Doi: 10.1002/slct.202203604.

Nuriye Doğan, Sevtap Çağlar Yavuz, Kader Sahin, Muge Didem Orhan, Hüseyin Kekec Muhammed, Seyma Calis, Fatma Öztürk Küp, Timucin Avsar, Senem Akkoc, Michael Tapera, Onur Sahin, Turker Kilic, Serdar Durdagi, Emin Saripinar ‘Synthesis, Characterization, Biological Activity and Molecular Modeling Studies of Novel Aminoguanidine Derivatives’ ChemistrySelect, 7(45), e202202819, 2022. Doi: 10.1002/slct.202202819.

Eyüp Basaran, Hatice Gamze Sogukomerogullari, Resit Cakmak, Senem Akkoc, Tugba Taskin-Tok, Ayşegül Köse ‘Novel Palladium(II), Nickel(II), Copper(II) and Iron(II) Complexes of Chiral Schiff Base: Synthesis, Characterization, Anticancer Activity and Molecular Docking Studies’ Bioorganic Chemistry, 129, 106176, 2022. Doi: 10.1016/j.bioorg.2022.106176.

Senem Akkoc, Halis Karatas, Muhammed Tilahun Muhammed, Zülbiye Kökbudak, Ahmet Ceylan, Faisal A. Almalki, Hamid Laaroussi, Taibi Ben Hadda, ‘Drug Design of New Therapeutic Agents: Molecular Docking, Molecular Dynamics Simulation, DFT and POM Analyses of New Schiff Base Ligands and Impact of Substituents on Bioactivity of Their Potential Antifungal Pharmacophore Site’ Journal of Biomolecular Structure and Dynamics, 41(14), 6695-6708, 2023. Doi: 10.1080/07391102.2022.2111360.

Ebru Önem, Gülsen Kendir, Senem Akkoç, Yalçın Erzurumlu, Muhammed Tilahun Muhammed, Ayşe Gül Özaydın ‘Biochemical contents and antiquorum sensing, antiproliferative activities of Opuntia ficus-indica (L.) Mill. Peel extract’ South African Journal of Botany, 150, 296-304, 2022. Doi: 10.1016/j.sajb.2022.07.024.

Hüseyin Kekeçmuhammed, Michael Tapera, Burak Tüzün, Senem Akkoç, Yunus Zorlu, Emin Sarıpınar, ‘Synthesis, molecular docking and antiproliferative activity studies of a thiazole-based compound linked to hydrazone moiety’ ChemistrySelect, 7(26), e202201502, 2022. Doi: 10.1002/slct.202201502.

Elif Bulat, Ertuğrul Gazi Sağlam, Celal Tuğrul Zeyrek, Senem Akkoç, Yunus Zorlu, Hakan Dal ‘Ni(II) complexes with 1,3,2,4-dithiadiphosphetane 2,4-disulfide-based ligands: structural insides, theoretical studies and anticancer activities’ Applied Organometallic Chemistry, 36(10), e6821, 2022. Doi: 10.1002/aoc.6821.

Eyüp Başaran, Reşit Çakmak, Senem Akkoç, Savaş Kaya ‘Combined experimental and theoretical analyses on design, synthesis, characterization, and in vitro cytotoxic activity evaluation of some novel imino derivatives containing pyrazolone ring’ Journal of Molecular Structure, 1265, 133427, 2022. Doi: 10.1016/j.molstruc.2022.133427.

İbrahim Evren Kıbrız, Senem Akkoç, Yusuf Sert, Ümit Çay, Şevket Hakan Üngören ‘Synthesis, Antiproliferative Activity, Molecular Docking Studies of Hydrazone Functionalised Thioparabanic Acid and Rhodanine Analogues’ Phosphorus, Sulfur, and Silicon and the Related Elements, 197 (9), 918-926, 2022. Doi: 10.1080/10426507.2022.2046578. SCI-E

Ihab Adnan Salman Al-Janabi, Sevtap Çağlar Yavuz, Semiha Köprü, Michael Tapera, Hüseyin Kekeçmuhammed, Senem Akkoç, Burak Tüzün, Şaban Patat, Emin Sarıpınar ‘Antiproliferative activity and molecular docking studies of new 4-oxothiazolidin-5-ylidene acetate derivatives containing guanylhydrazone moiety’ Journal of Molecular Structure, 1258, 132627, 2022. Doi: 10.1016/j.molstruc.2022.132627. SCI, SCI-E

Mahmut Devim, Senem Akkoç, Celal Tuğrul Zeyrek, Halime Güzin Aslan, Zülbiye Kökbudak, ‘Design, synthesis, in vitro antiproliferative activity properties, quantum chemical and molecular docking studies of novel Schiff bases incorporating pyrimidine nucleus’ Journal of Molecular Structure, 1254, 132421, 2022. Doi:

Zülbiye Kökbudak, Senem Akkoç, Halis Karataş, Burak Tüzün, Güzin Aslan, ‘In Silico and In Vitro Antiproliferative Activity Assessment of New Schiff Bases’ ChemistrySelect, 7(3), e202103679, 2022. Doi: 10.1002/slct.202103679

Obinna C. Okpareke, William Henderson, Senem Akkoç, Burak Coban ‘Platinum(II), palladium(II) and nickel(II) complexes of bisthiourea ligands’ Inorganica Chimica Acta, 531, 120707, 2022. SCI, Doi: 10.1016/j.ica.2021.120707

Ebru Önem, Burak Tüzün, Senem Akkoç ”Anti-quorum sensing activity in Pseudomonas aeruginosa PA01 of benzimidazolium salts: Electronic, spectral and structural investigations as theoretical approach” Journal of Biomolecular Structure & Dynamics, 40(15), 6845-6856, 2022. Doi: 10.1080/07391102.2021.1890222.

Ertuğrul Gazi Sağlam, Senem Akkoç, Nurcan Acar, Hakan Dal, Özgür Tutsak, Leyla Açık, Süheyla Pınar Çelik, ”New Heterobimetallic Ferrocenyl Dithiophosphonato Cd(II) and Hg(II) Complexes: DNA Interactions, Antimicrobial and Anticancer Activity Studies of the Cd(II) Complexes” ChemistrySelect, 2021.

Burak Coban, Engin Saka, Sedef Şentürk, Ufuk Yıldız, Senem Akkoç ”DNA Interactions and Antiproliferative Activity Studies of Octahedral Nickel Complexes of Two Extended Phenanthrolines” ChemistrySelect, 6(34), 9012-9023, 2021.

Senem Akkoç, Burak Tüzün, Ayhan Özalp, Zülbiye Kökbudak ”Investigation of structural, electronical and in vitro cytotoxic activity properties of some heterocyclic compounds” Journal of Molecular Structure, 1246, 131127, 2021. Doi:

Senem Akkoç, ”Importance of some factors on the Suzuki-Miyaura cross-coupling reaction” Journal of the Chinese Chemical Society, 68, 942-951, 2021. Doi: 10.1002/jccs.202000351

Sevtap Çağlar Yavuz, Senem Akkoç, Burak Tüzün, Onur Şahin, Emin Sarıpınar ”Efficient synthesis and molecular docking studies of new pyrimidine-chromeno hybrid derivatives as potential antiproliferative agents” Synthetic Communications, 51(14), 2135-2159, 2021. Doi: 10.1080/00397911.2021.1922920

Ertuğrul Gazi Sağlam, Senem Akkoç, Yunus Zorlu, Elif Bulat, Aziz Akgün ‘New Phenanthroline Nickel(II) Organodithio-Phosphorus Complexes: Syntheses, Structural Characterizations and In Vitro Cytotoxic Activity Studies’ Polyhedron, 115097, 2021.

Ertuğrul Gazi Sağlam, Senem Akkoç, Celal Tuğrul Zeyrek, Hakan Dal, Özgür Tutsak ”New heterobimetallic nickel(II) ferrocenyldithiophosphonato complexes: syntheses, characterization, antiproliferative activity studies and X-ray, DFT, molecular docking on trans-bis-[O-3-methyl-1-butyl-(ferrocenyl)dithiophosphonato]nickel(II)” Inorganica Chimica Acta, 514, 119991, 2021. Doi:

Senem Akkoç ‘Design, synthesis, characterization and in vitro cytotoxic activity evaluation of 1,2-disubstituted benzimidazole compounds’ Journal of Physical Organic Chemistry, 34, e4125, 2021. DOI:10.1002/poc.4125. SCI, SCIE

Feyza Tınmaz, İlhan Özer İlhan, Senem Akkoç ‘Preparation and Properties of Some New Pyrazole Derivatives’ Organic Preparations and Procedures International, 53 (1), 89-94, 2021. Doi: 10.1080/00304948.2020.1846449. SCIE

Gulsen Turkoglu, Senem Akkoç ”Substituent-Dependent Absorption Spectra, Electrochemical and Antiproliferative Activity Studies of Some 3-(4-(Benzyloxy)phenyl)-5-(4-methoxyphenyl)-1-(substitutedphenyl)formazans” ChemistrySelect, 5 (43), 13469-13476, 2020. Doi.org/10.1002/slct.202003498. SCIE

Bahar Caymaz, Ufuk Yıldız, Senem Akkoç, Zuhal Gerçek, Abdurrahman Şengül, Burak Coban ‘Synthesis, characterization, and antiproliferative activity studies of novel benzimidazole-imidazopyridine conjugates as DNA groove binders’ ChemistrySelect, 5 (28), 8465-8474, 2020. doi.org/10.1002/slct.202001580. SCIE

Senem Akkoç, Sevtap Çağlar Yavuz, Burçin Türkmenoğlu, İlhan Özer İlhan, Mehmet Akkurt, ‘Single Crystal, DFT and Docking Studies of a Benzimidazolium Salt’ Crystallography Reports, 65 (7) 1173-1178, 2020. Doi: 10.1134/S1063774520070032. SCI, SCIE

Senem Akkoç, Burak Tüzün, İlhan Özer İlhan, Mehmet Akkurt ‘Investigation of structural, spectral, electronic, and biological properties of 1,3-disubstituted benzimidazole derivatives’ Journal of Molecular Structure, vol: 1219, 128582, 2020. Doi: . SCI, SCIE

Bahrouz Abulhasanov, Ufuk Yıldız, Senem Akkoç, Burak Coban ‘Synthesis, Characterization, Duplex-DNA Interactions and Anticancer Activities of Novel Octahedral [Ni(phen)2(dppz-idzo)]2+ and [Co(phen)2(dppz-idzo)]3+ Complexes’ Applied Organometallic Chemistry, 34, e5866, 2020. https://doi.org/10.1002/aoc.5866. SCI, SCIE

Sevtap Çağlar Yavuz, Senem Akkoç, Burçin Türkmenoğlu, Emin Sarıpınar, ‘Synthesis of Novel Heterocyclic Compounds Containing Pyrimidine Nucleus Using the Biginelli Reaction: Antiproliferative Activity and Docking Studies’ Journal of Heterocyclic Chemistry, 57, 2615-2627, 2020.

Gulsen Turkoglu, Senem Akkoç, ‘Synthesis, optical, electrochemical and antiproliferative activity studies of novel formazan derivatives’ Journal of Molecular Structure, 1211, 128028, 2020. Doi: 10.1016/j.molstruc.2020.128028

Ufuk Yıldız, İrfan Kandemir, Fusun Comert, Senem Akkoç, and Burak Coban, “Synthesis of naphthalimide derivatives with potential anticancer activity, their comparative ds- and G-quadruplex-DNA binding studies and related biological activities” Molecular Biology Reports, 47(3), 1563-1572, 2020. Doi: 10.1007/s11033-019-05239-y. SCI, SCI-E

Halime Güzin Aslan, Senem Akkoç, Zülbiye Kökbudak ‘Anticancer activities of various new metal complexes prepared from a Schiff base on A549 cell line’ Inorganic Chemistry Communications, 111, 107645, 2020. Doi: . SCI

Zülbiye Kökbudak, Murat Saracoglu, Senem Akkoç, Zeynep Çimen, M. Izzettin Yılmazer, Fatma Kandemirli ‘Synthesis, cytotoxic activity and quantum chemical calculations of new 7-thioxopyrazolo[1,5-f]pyrimidin-2-one derivatives’ Journal of Molecular Structure, 1202, 127261, 2020. Doi: . SCI

Zülbiye Kökbudak, Halime Güzin Aslan, Senem Akkoç, ‘New Schiff Bases Based on 1-Aminopyrimidine-2-(1H)-one: Design, Synthesis, Characterization and Theoretical Calculations’ Heterocycles, 100 (3), 440-449, 2020. Doi: 10.3987/COM-20-14221. SCI-Exp

Yetkin Gök, Senem Akkoç, Özlem Özeroğlu Çelikal, İlknur Özdemir and Selami Günal ‘In Vitro Antimicrobial Studies of Naphthalen-1-ylmethyl Substituted Silver N-Heterocyclic Carbene Complexes’ Arabian Journal of Chemistry, 12, 2513-2518, 2019. .

Sevtap Çağlar Yavuz, Senem Akkoç, Emin Sarıpınar ‘The cytotoxic activities of imidazole derivatives prepared from various guanylhydrazone and phenylglyoxal monohydrate’ Synthetic Communications, 49 (22), 3198-3209, 2019. Doi: . SCI-E

Senem Akkoç, Veysel Kayser, İlhan Özer İlhan ‘Synthesis and in vitro Anticancer Evaluation of Some Benzimidazolium Salts’ Journal of Heterocyclic Chemistry, 56, 2934-2944, 2019. Doi: 10.1002/jhet.3687

Senem Akkoç ‘Antiproliferative activities of 2-hydroxyethyl substituted benzimidazolium salts and their palladium complexes against human cancerous cell lines’ Synthetic Communications, 49 (21), 2903-2914, 2019. Doi: 10.1080/00397911.2019.1650187. SCI-E

Funda Özdemir, İlhan Özer İlhan, Senem Akkoç ‘Synthesis and characterization of new 4,5-dihydropyrazol-1-yl derivatives’ Synthetic Communications, 49 (18), 2417-2424, 2019. . SCI-E

Senem Akkoç ‘Derivatives of 1-(2-(Piperidin-1-yl)ethyl)-1H-benzo[d]imidazole: Synthesis, Characterization, Determining of Electronic Properties and Cytotoxicity Studies’ ChemistrySelect, 17 (4) 4938-4943, 2019. Doi: 10.1002/slct.201900353. SCI

Ufuk Yıldız, Abdurrahman Şengül, İrfan Kandemir, Fusun Comert, Senem Akkoç, and Burak Coban, ‘The comparative study of the DNA binding and biological activities of the quaternized dicnq as a dicationic form and its platinum(II) heteroleptic cationic complex’ Bioorganic Chemistry, 87, 70-77, 2019. Doi:

Zeynep Çimen, Senem Akkoç, Zülbiye Kökbudak ‘Reactions of Amino Pyrimidine Derivatives with Chloroacetyl and Isophthaloyl Chlorides’ Heteroatom Chemistry, 29, e21458, 2018.

Halime Güzin Aslan, Senem Akkoç, Zülbiye Kökbudak and Lütfiye Aydın ‘Synthesis, characterization, antimicrobial and catalytic activity of a new Schiff base and its metal(II) complexes’ Journal of the Iranian Chemical Society, 14, 2263-2273, 2017. Doi: 10.1007/s13738-017-1163-4.

Ziya Sahin, Senem Akkoc, Ronald Neeleman, Jonathan Haines, Veysel Kayser ‘Nile Red Fluorescence Spectrum Decomposition Enables Rapid Screening of Large Protein Aggregates in Complex Biopharmaceutical Formulations Like Influenza Vaccines’ Vaccine, 35, 3026-3032, 2017. doi: 10.1016/j.vaccine.2017.04.066.

Ziya Sahin, Senem Akkoç, İlhan Özer İlhan, Veysel Kayser ‘Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-Carbon Bond-Forming Reactions’ Journal of Visualized Experiments (JoVE), 2017. doi: 10.3791/54932.

Senem Akkoç, Veysel Kayser, İlhan Özer İlhan, David E. Hibbs, Yetkin Gök, Peter A. Williams, Bryson Hawkins, Felcia Lai ‘New compounds based on a benzimidazole nucleus: synthesis, characterization and cytotoxic activity against breast and colon cancer cell lines’ Journal of Organometallic Chemistry, Special Issue, 839, 98-107, 2017.

Senem Akkoç, İlhan Özer İlhan, Yetkin Gök, Veysel Kayser ‘Carbon-carbon bond formation catalyzed by PEPPSI Pd-NHC’ Inorganica Chimica Acta, 461, 52-56, 2017. .

Senem Akkoç, Yetkin Gök, Hulya Erdogan and Sevil Albayrak ‘Biological activity evaluation of novel N-heterocyclic carbene precursors’ International Journal of Pharmaceutical Sciences and Research, 8(1), 262-267, 2017. Doi: 10.13040/IJPSR.0975-8232.8(1).262-67.

Senem Akkoç, İlhan Özer İlhan, Yetkin Gök, Parth J. Upadhyay and Veysel Kayser ‘In vitro cytotoxic activities of new silver and PEPPSI palladium N-heterocyclic carbene complexes derived from benzimidazolium salts’ Inorganica Chimica Acta, 449, 75-81, 2016. .

Senem Akkoç, Yetkin Gök, İlhan Özer İlhan and Veysel Kayser ‘N-Methylphthalimide substituted benzimidazolium salts and PEPPSI Pd-NHC complexes: synthesis, characterization and catalytic activity in carbon-carbon bond forming reactions’ Beilstein Journal of Organic Chemistry, 12, 81-88, 2016. Doi: 10.3762/bjoc.12.9.

Yakup Sarı, Senem Akkoç, Yetkin Gök, Vicki Sifniotis, İlknur Özdemir, Selami Günal and Veysel Kayser ‘Benzimidazolium based novel silver N-heterocyclic carbene complexes: synthesis, characterisation and in vitro antimicrobial activity’ Journal of Enzyme Inhibition and Medicinal Chemistry, 31(6), 1527-1530, 2016. Doi: 10.3109/14756366.2016.1156102.

Senem Akkoç, Yetkin Gök, İlhan Özer İlhan and Veysel Kayser ‘In situ generation of efficient palladium N-heterocyclic carbene catalysts using benzimidazolium salts for the Suzuki-Miyaura cross-coupling reaction’ Current Organic Synthesis, 13(5), 761-766, 2016. Doi: 10.2174/1570179413666151218200334

Yetkin Gok, Senem Akkoc, Hulya Erdogan and Sevil Albayrak ‘In vitro antimicrobial studies of new benzimidazolium salts and silver N-heterocyclic carbene complexes’ Journal of Enzyme Inhibition and Medicinal Chemistry, 31(6), 1322-1327, 2016. Doi: 10.3109/14756366.2015.1132210.

Senem Akkoç and Yetkin Gök ‘Dichlorido(3-chloropyridine-N)[1,3-dialkylbenzimidazol-2-ylidene]palladium(II) complexes: Synthesis, characterization and catalytic activity in the arylation reaction’ Inorganica Chimica Acta, 429, 34-38, 2015. Doi:

Senem Akkoç and Yetkin Gök ‘Catalytic Activities in Direct Arylation of Novel Palladium N-Heterocyclic Carbene Complexes’ Applied Organometallic Chemistry, 28, 854-860, 2014. Doi:

Yetkin Gök, Senem Akkoç, Mehmet Akkurt and Muhammad Nawaz Tahir ‘Imidazole, Pyrimidine and Diazepine Containing Heteroaryl-Substituted Heterocyclic Salts as Efficient Ligand Precursors for Mizoroki-Heck Coupling Reaction: Synthesis, Structural Characterization and Catalytic Activities’ Journal of the Iranian Chemical Society, 11, 1767-1774, 2014. Doi: 10.1007/s13738-014-0449-z

Senem Akkoç, Yetkin Gök, Mehmet Akkurt and M. Nawaz Tahir ‘Catalytic Activities in the Direct C5 Arylation of Novel Palladium N-Heterocyclic Carbene Complexes Containing Benzimidazol-2-ylidene Nucleus’ Inorganica Chimica Acta, 413, 221-230, 2014. Doi: 10.1016/j.ica.2014.01.015

Yetkin Gök, Senem Akkoç, Sevil Albayrak, Mehmet Akkurt and M. Nawaz Tahir ‘N-Phenyl Substituted Carbene Precursors and Their Silver Complexes: Synthesis, Characterization and Antimicrobial Activities’ Applied Organometallic Chemistry, 28(4), 244-251, 2014. Doi: 10.1002/aoc.3116

 

Aydin Aktaş, Senem Akkoç and Yetkin Gök ‘Palladium Catalyzed Mizoroki-Heck And Suzuki-Miyaura Reactions Using Napthalenomethyl-Substituted Imidazolidin-2-ulidene Ligands in Aqueous Media’ Journal of Coordination Chemistry, 66 (16), 2901-2909, 2013. Doi: 10.1080/00958972.2013.819092

Senem Akkoç and Yetkin Gök ‘Synthesis And Characterization of 1-Phenyl-3-Alkylbenzimidazol-2-ylidene Salts And Their Catalytic Activities in The Heck And Suzuki Cross-Coupling Reactions’ Journal of Coordination Chemistry, 66 (8), 1396-1404, 2013. Doi: 10.1080/00958972.2013.786053